LEQVIO (INCLISIRAN)
LEQVIO (Inclisiran) is a potent cholesterol lowering drug indicated for use in people with a type of cardiovascular disease (CVD) called atherosclerotic cardiovascular disease (ASCVD), and Familial hypercholesterolemia (FH). Lots of fun acronyms.
Currently we are beyond the unbranded phase and full steam ahead in branded, under the name LEQVIO. The projects shown here span the life of the brand so far, from unbranded to branded, with DTC and HCP samples.
CHOLESTEROL SUCCESS :30 SECOND SPOT
This LEQVIO commercial was released summer of 2023. There are 2 versions of this spot. The version reflected here is the second “pool out” spot. I did not work on version 1 beyond making edits, but was responsible for writing this version. I saw this all the way through into finalized animatics. Eventually, when I left McCann, my team took it over. The spot was shot in Australia during the winter of 2023.
Writer: James Tarzian
Art Direction: Jonathan Hoffmann
Creative Direction: Aaron Alamo & Joan Wildermuth
THAT LEQVIO FEELING :60 SECOND CINEMATIC
The following video is a cinematic that was used in testing for a campaign refresh. Over the summer of 2022, our client tasked us with rethinking the current LEQVIO DTC TV spot. The main idea was to show how success with LEQVIO can look. Our concept highlights how it feels to reach your cholesterol target after years and years of disappointment. This option came close and was a creative team favorite, but was ultimately not chosen.
Writer: James Tarzian
Art Director: Jason Bitner
INCLISIRAN UNBRANDED U.S. SITE
The unbranded site: Breakthecvdtrend.com, is
patient-friendly and educational. Its purpose is to make people aware of how there will be more and more deaths from CVD if we don't make major treatment changes now.
Writer: James Tarzian
Art Director: Jason Kim
US WEBSITE MYTH QUIZ
Can you separate myth from fact? This unbranded DTC myth quiz is an educational tool that lives on Breakthecvdtrend.com. Users are presented with a series of statements which they click and drag into 1 of 2 categories, “Myth” or “Fact”. Statements are randomly generated and shuffle each time you replay. At the end of the quiz, users are given the correct answers and a score.
Writer: James Tarzian
Art Director: Tasia Dedenbach

INCLISIRAN DIGITAL UNBRANDED SALES AID
Click on the image to view the interactive pdf
This sales aid was made as both a print and digital piece. It is intended to educate physcians in the ASCVD/CVD space, and to raise awareness about how CVD is still the #1 killer of people in the United States, and growing.















